GFAP Mouse Monoclonal Antibody [Clone ID: GA-8]

CAT#: AM20624PU-N

GFAP mouse monoclonal antibody, clone GA-8, Purified


USD 405.00

2 Weeks*

Size
    • 100 ug

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Specifications

Product Data
Clone Name GA-8
Applications IHC, WB
Recommended Dilution Western Blot: 0.5 - 1 μg/ml.
Immunohistochemistry on frozen sections: 0.5 - 1 μg/ml.
Immunohistochemistry on paraffin sections: 0.4 - 1 μg/ml.
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen GFAP from pig spinal cord.
Specificity This antibody reacts to GFAP.
Formulation 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.
State: Purified
State: Lyphilized purified Ig fraction
Reconstitution Method Restore with 1.2% sodium acetate or neutral PBS
Concentration lot specific
Purification Affinity chromatography
Storage Prior to reconstitution store at -20°C.
Following reconstitution store undiluted at 2-8°C for one month
or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens glial fibrillary acidic protein (GFAP), transcript variant 2
Background GGlial fibrillary acidic protein (GFAP) is an intermediate-filament (IF) protein that is highly specific for cells of astroglial lineage, although its tissue-specific role is speculative. GFAP has been located in rat kidney glomeruli and peritubular fibroblasts, leydig cells of testis, skin keratinocytes, osteocytes of bones, chondrocytes of epiglottis, bronchus, and stellate-shaped cells of the pancreas and liver. Its expression is essential for normal white matter architecture and blood-brain barrier integrity, and its absence leads to late-onset CNS dysmyelination. GFAP has also been shown to play a role in mitosis by adjusting the filament network present in the cell. During mitosis, there is an increase in the amount of phosphorylated GFAP, and a movement of this modified protein to the cleavage furrow.
Synonyms Glial Fibrillary Acidic Protein
Reference Data
Protein Families ES Cell Differentiation/IPS

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.