Growth Hormone (GH1) Mouse Monoclonal Antibody [Clone ID: GA-8]

CAT#: AM20625PU-N

Growth Hormone (GH1) mouse monoclonal antibody, clone GA-8, Purified

Specifications

Product Data

• Clone Name: GA-8
• Applications: IHC
• Recommended Dilution: Immunohistochemistry on paraffin sections: 2 - 4 μg/ml.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant hGH.
• Specificity: This antibody reacts to Somatotropin.
• Formulation: 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.
  State: Purified
  State: Lyphilized purified Ig fraction
• Reconstitution Method: Restore with 1.2% sodium acetate or neutral PBS
• Concentration: lot specific
• Purification: Affinity chromatography
• Storage: Prior to reconstitution store at -20°C.
  Following reconstitution store undiluted at 2-8°C for one month
  or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens growth hormone 1 (GH1), transcript variant 1
• Database Link:
  Entrez Gene 2688 Human
• Background: Growth Hormone (GH) is mapped to 17q22-q24. Human growth hormone has a molecular mass of 22,005 and contains 191 amino acid residues with 2 disulfide bridges. It binds two receptor molecules and thereby induces signal transduction through receptor dimerization. At high concentrations, GH acts as an antagonist because of a large difference in affinities at the respective binding sites.
• Synonyms: Pituitary growth hormone, Growth hormone 1, HGH

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Neuroactive ligand-receptor interaction