HSP90AB1 Mouse Monoclonal Antibody [Clone ID: SJ-90]

CAT#: AM20628PU-N

HSP90AB1 mouse monoclonal antibody, clone SJ-90, Purified

Specifications

Product Data

• Clone Name: SJ-90
• Applications: WB
• Recommended Dilution: Western Blot: 2 - 4 μg/ml.
• Reactivities: Chicken, Frog, Human, Mouse, Rabbit, Rat
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Heat shock protein 90 (HSP90) from the water mold Achlya
  ambisexualis
• Specificity: This antibody reacts to Heat Shock Protein 90.
• Formulation: 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.
  State: Purified
  State: Lyphilized purified Ig fraction
• Reconstitution Method: Restore with 1.2% sodium acetate or neutral PBS
• Concentration: lot specific
• Purification: Affinity chromatography
• Storage: Prior to reconstitution store at -20°C.
  Following reconstitution store undiluted at 2-8°C for one month
  or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens heat shock protein 90kDa alpha family class B member 1 (HSP90AB1), transcript variant 2
• Database Link:
  Entrez Gene 15516 MouseEntrez Gene 301252 RatEntrez Gene 3326 Human
• Background: Heat Shock Protein 90 (HSP70) exists in multiple forms in mammalian cells. It has a unique 30-amino acid N terminus instead of the 223-amino acid TP/geldanamycin-binding domain found at the N terminus of full-length HSPCA, which contains 732 amino acids. Functional proteomic screens reveal an essential extracellular role for hsp90-alpha in cancer cell invasiveness.
• Synonyms: HSP90AB1, HSP90B, HSPC2, HSPCB, HSP84, HSP-90, HSP-84, Heat shock protein HSP 90-beta, HSP84, HSP-84, HSP90AA1, HSP90A, HSPC1, HSPCA, HSP86, HSP-86, Renal carcinoma antigen NY-REN-38, Heat shock protein HSP 90-alpha, HSP86, HSP-86

Reference Data

• Protein Families: Druggable Genome, Stem cell - Pluripotency
• Protein Pathways: Antigen processing and presentation, NOD-like receptor signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer