N Cadherin (CDH2) Mouse Monoclonal Antibody [Clone ID: NC-17]

CAT#: AM20646PU-N

N Cadherin (CDH2) mouse monoclonal antibody, clone NC-17, Purified


USD 405.00

2 Weeks*

Size
    • 100 ug

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Specifications

Product Data
Clone Name NC-17
Applications IHC, WB
Recommended Dilution Western Blot: 2 μg/ml.
Immunohistochemistry on frozen sections: 4 μg/ml.
Reactivities Chicken, Human, Mouse, Rabbit, Rat
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Affinity purified chicken heart A-CAM.
Specificity This antibody reacts to Cadherin-2.
Formulation 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3 (all per vial) as preservative.
State: Purified
State: Lyphilized purified Ig fraction
Reconstitution Method Restore with 1 ml neutral PBS to achieve stock solutiom of 0.1 mg/ml
Concentration lot specific
Purification Affinity chromatography
Storage Prior to reconstitution store at -20°C.
Following reconstitution store undiluted at 2-8°C for one month
or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens cadherin 2 (CDH2), transcript variant 1
Background N-cadherin (NCAD) is a member of the cadherin cell-cell adhesion receptor family that includes P-, E-,and R-cadherin and liver cell adhesion molecule (L-CAM). N-Cadherin,, also known as Cadherin-2,encodes a 907-amino acid protein that includes a 159-amino acid signal sequence. Human and mouse nucleotide sequences are 96% identical. Mouse Ncad gene consists of 16 exons dispersed over more than 200 kb of genomic DNA. Human N-cadherin gene contains 16 exons and its sequence is highly similar to both the mouse NCAD gene (including the large first and second introns) and other cadherin genes. N-cadherin is mapped to 18q11.2. Cadherin regulates dendritic spine morphogenesis.
Synonyms CDH2, CDHN, NCAD, Neural cadherin, CDw325, Cadherin N, N-Cadherin
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways Arrhythmogenic right ventricular cardiomyopathy (ARVC), Cell adhesion molecules (CAMs)

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.