Paxillin (PXN) (C-term) Mouse Monoclonal Antibody [Clone ID: PAX-14]

CAT#: AM20658PU-N

Paxillin (PXN) (C-term) mouse monoclonal antibody, clone PAX-14, Purified


USD 405.00

2 Weeks*

Size
    • 100 ug

Product Images

Specifications

Product Data
Clone Name PAX-14
Applications IF, WB
Recommended Dilution Western Blot: 1 - 2 μg/ml.
Immunocytochemistry.
Reactivities Chicken, Human, Mouse, Rat
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen C-terminal part of recombinant chicken paxillin (amino acids
305-559)
Specificity This antibody reacts to Paxillin.
Formulation 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.
State: Purified
State: Lyphilized purified Ig fraction
Reconstitution Method Restore with 1.2% sodium acetate or neutral PBS
Concentration lot specific
Purification Affinity chromatography
Storage Prior to reconstitution store at -20°C.
Following reconstitution store undiluted at 2-8°C for one month
or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens paxillin (PXN), transcript variant 2
Background The paxillin gene can be alternatively spliced to include 1 of 2 alternative exons, generating beta and gamma isoforms. Paxillin is a 68-kDa focal adhesion protein that is phosphorylated on tyrosine residues in fibroblasts in response to transformation by v-src, treatment with platelet-derived growth factor, or cross-linking of integrins. The 68-kD protein (paxillin) is a cytoskeletal component that localizes to the focal adhesions at the ends of actin stress fibers in chicken embryo fibroblasts. It is also present in the focal adhesions of Madin-Darby bovine kidney (MDBK) epithelial cells but is absent, like talin, from the cell-cell adherens junctions of these cells.
Synonyms FLJ16691
Reference Data
Protein Families Druggable Genome, Stem cell - Pluripotency
Protein Pathways Chemokine signaling pathway, Focal adhesion, Leukocyte transendothelial migration, Regulation of actin cytoskeleton, VEGF signaling pathway

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.