P Glycoprotein (ABCB1) Mouse Monoclonal Antibody [Clone ID: PG-13]

CAT#: AM20661PU-N

P Glycoprotein (ABCB1) mouse monoclonal antibody, clone PG-13, Purified

Specifications

Product Data

• Clone Name: PG-13
• Applications: IF, IHC, WB
• Recommended Dilution: Western Blot: 0.5 - 1 μg/ml.
  Immunohistochemistry on paraffin and frozen sections: 1 - 2 μg/ml.
  Immunocytochemistry.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: A mixture of human and hamster drug-resistant whole cells and crude plasma membranes.
• Specificity: This antibody reacts to CD243 / MDR1.
• Formulation: 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.
  State: Purified
  State: Lyphilized purified Ig fraction
• Reconstitution Method: Restore with 1.2% sodium acetate or neutral PBS
• Concentration: lot specific
• Purification: Affinity chromatography
• Storage: Prior to reconstitution store at -20°C.
  Following reconstitution store undiluted at 2-8°C for one month
  or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens ATP binding cassette subfamily B member 1 (ABCB1)
• Database Link:
  Entrez Gene 5243 Human
• Background: P-Glycoprotein,, also known as Multidrug Resistance 1 (MDR1), is one of the ATP-binding cassette transporters family. P-glycoprotein-1 is involved in the transport of 3 of these protease inhibitors in vitro.MDR1 gene is mapped to the 7q21.1 by in situ hybridization. The MDR1 gene product, P-glycoprotein,mediates the transport of the cardiac glycoside, digoxin.
• Synonyms: Multidrug resistance protein 1, P-glycoprotein 1, ABCB1, PGY1

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: ABC transporters