P Glycoprotein (ABCB1) Mouse Monoclonal Antibody [Clone ID: PG-13]

CAT#: AM20661PU-N

P Glycoprotein (ABCB1) mouse monoclonal antibody, clone PG-13, Purified


USD 405.00

2 Weeks*

Size
    • 100 ug

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Specifications

Product Data
Clone Name PG-13
Applications IF, IHC, WB
Recommended Dilution Western Blot: 0.5 - 1 μg/ml.
Immunohistochemistry on paraffin and frozen sections: 1 - 2 μg/ml.
Immunocytochemistry.
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen A mixture of human and hamster drug-resistant whole cells and crude plasma membranes.
Specificity This antibody reacts to CD243 / MDR1.
Formulation 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.
State: Purified
State: Lyphilized purified Ig fraction
Reconstitution Method Restore with 1.2% sodium acetate or neutral PBS
Concentration lot specific
Purification Affinity chromatography
Storage Prior to reconstitution store at -20°C.
Following reconstitution store undiluted at 2-8°C for one month
or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens ATP binding cassette subfamily B member 1 (ABCB1)
Background P-Glycoprotein,, also known as Multidrug Resistance 1 (MDR1), is one of the ATP-binding cassette transporters family. P-glycoprotein-1 is involved in the transport of 3 of these protease inhibitors in vitro.MDR1 gene is mapped to the 7q21.1 by in situ hybridization. The MDR1 gene product, P-glycoprotein,mediates the transport of the cardiac glycoside, digoxin.
Synonyms Multidrug resistance protein 1, P-glycoprotein 1, ABCB1, PGY1
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways ABC transporters

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.