MAPT Mouse Monoclonal Antibody [Clone ID: TAU-93]

CAT#: AM20671PU-N

MAPT mouse monoclonal antibody, clone TAU-93, Purified

Specifications

Product Data

• Clone Name: TAU-93
• Applications: IHC, WB
• Recommended Dilution: Western Blot: 0.5 - 1 μg/ml.
  Immunohistochemistry on paraffin sections: 1 - 2 μg/ml.
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Bovine microtubule-associated proteins (MAPs).
• Specificity: This antibody reacts to MAPT / TAU.
• Formulation: 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.
  State: Purified
  State: Lyphilized purified IgG fraction
• Reconstitution Method: Restore with 1.2% sodium acetate or neutral PBS
• Concentration: lot specific
• Purification: Affinity chromatography
• Storage: Prior to reconstitution store at -20°C.
  Following reconstitution store undiluted at 2-8°C for one month
  or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Database Link:
  Entrez Gene 281296 Bovine
• Background: The microtubule-associated proteins (MAPs) coassemble with tubulin into microtubules in vitro.Microtubule-associated protein tau appears to be enriched in axons. Tau are composed of 352 to 441 amino acids. The isoforms differ from each other by the presence or absence of 29-amino acid or 58-amino acid inserts located in the N terminus and a 31-amino repeat located in the C terminus. tau is important in establishing and maintaining neuronal morphology and is a major component of the neurofibrillary tangles (NFTs) characteristic of Alzheimer's brain. Microtubule-associated protein tau (MTBT1) is mapped to chromosome 17q21.
• Synonyms: MAPTL, MTBT1, Microtubule-associated protein tau, PHF-tau, Neurofibrillary tangle protein, Paired helical filament-tau