TPM1 (36Da) Mouse Monoclonal Antibody [Clone ID: TM-36]

CAT#: AM20676PU-N

TPM1 (36Da) mouse monoclonal antibody, clone TM-36, Purified

Specifications

Product Data

• Clone Name: TM-36
• Applications: IF, IHC, WB
• Recommended Dilution: Western Blot: 0.5 - 1 μg/ml.
  Immunohistochemistry on frozen sections: 1 - 2 μg/ml.
• Reactivities: Chicken, Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Chicken gizzard tropomyosin
• Specificity: This antibody reacts to Tropomyosin-1 (TPM1).
• Formulation: 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.
  State: Purified
  State: Lyphilized purified Ig fraction
• Reconstitution Method: Restore with 1.2% sodium acetate or neutral PBS
• Concentration: lot specific
• Purification: Affinity chromatography
• Storage: Prior to reconstitution store at -20°C.
  Following reconstitution store undiluted at 2-8°C for one month
  or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens tropomyosin 1 (alpha) (TPM1), transcript variant Tpm1.5
• Database Link:
  Entrez Gene 22003 MouseEntrez Gene 24851 RatEntrez Gene 7168 Human
• Background: The tropomyosins are a family of actin filament binding proteins. These proteins were first isolated from skeletal muscle, but later identified in many nonmuscle tissues. Tropomyosins are ubiquitous proteins of 35 to 45 kD associated with the actin filaments of myofibrils and stress fibers. Vertebrates have at least 4 different tropomyosin genes; in humans, they are named TPM1, TPM2, TPM3, and TPM4. Tropomyosins expressed as different isoforms in muscle and non-muscle cells.
• Synonyms: Tropomyosin alpha-1 chain, Alpha-tropomyosin, TMSA, C15orf13

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)