VEGF Receptor 1 (FLT1) Mouse Monoclonal Antibody [Clone ID: V12]
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Specifications
Product Data | |
Clone Name | V12 |
Applications | IF, IHC, WB |
Recommended Dilution | Western Blot: 1 - 2 μg/ml. Immunohistochemistry on frozen sections: 2 - 4 μg/ml. Immunocytochemistry. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Recombinant human VEGF-1 receptor |
Specificity | This antibody reacts to VEGFR-1. |
Formulation | 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative State: Purified State: Lyphilized purified Ig fraction |
Reconstitution Method | Restore with 1.2% sodium acetate or neutral PBS |
Concentration | lot specific |
Purification | Affinity chromatography |
Storage | Prior to reconstitution store at -20°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | Homo sapiens fms related tyrosine kinase 1 (FLT1), transcript variant 1 |
Database Link | |
Background | VEGFR1, also known as FMS-related tyrosine kinase 1(FLT1). Oncogene FLT belongs to the src gene family and is related to oncogene ROS . Like other members of this family, it shows tyrosine protein kinase activity that is important for the control of cell proliferation and differentiation. FLT is mapped to 13q12. VEGF receptor 1 signaling is essential for osteoclast development and bone marrow formation in colony-stimulating factor 1-deficient mice. |
Synonyms | VEGFR1, FLT1, FLT, FRT, VEGF Receptor 1 |
Reference Data | |
Protein Families | Druggable Genome, Protein Kinase, Secreted Protein |
Protein Pathways | Cytokine-cytokine receptor interaction, Endocytosis, Focal adhesion |
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