beta Actin (ACTB) Mouse Monoclonal Antibody [Clone ID: AC-15]

CAT#: AM20687PU-N

beta Actin (ACTB) mouse monoclonal antibody, clone AC-15, Purified


USD 405.00

2 Weeks*

Size
    • 100 ug

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Other products for "ACTB"

Specifications

Product Data
Clone Name AC-15
Applications IHC, IP, WB
Recommended Dilution Western Blot: 0.25-0.5 μg/ml.
Immunohistochemistry on Paraffin Sections: 0.5-1 μg/ml.
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Slightly modified beta-cytoplasmic actin N-terminal peptide,
Ac-Asp-Asp-Asp-Ile-Ala-Ala-Leu-Val-Ile-Asp-Asn-Gly-Ser-Gly-Lys, conjugated to KLH.
Specificity This antibody reacts to Actin beta.
Formulation PBS
State: Purified
State: Liquid purified Ig fraction
Preservative: 0.02% Sodium Azide
Reconstitution Method Restore with 1.2% sodium acetate or neutral PBS.
Concentration lot specific
Purification Affinity Chromatography
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens actin beta (ACTB)
Background The primary site of action of cytochalasin B on cell motility processes is beta-actin. Habets et al. (1992) generated hybrids that harbor only specific regions of human chromosome 7 and assigned the ACTB locus to 7p15-p12. ACTB and the other assigned beta-actin-related sequences are dispersed over at least four different chromosomes including one locus assigned to the X chromosome. A mutation of beta-actin that alters depolymerization dynamics is associated with autosomal dominant developmental malformations, deafness, and dystonia.
Synonyms Actin cytoplasmic 1, Beta-Actin
Reference Data
Protein Families ES Cell Differentiation/IPS
Protein Pathways Adherens junction, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, Focal adhesion, Hypertrophic cardiomyopathy (HCM), Leukocyte transendothelial migration, Pathogenic Escherichia coli infection, Regulation of actin cytoskeleton, Tight junction, Vibrio cholerae infection, Viral myocarditis

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.