gamma Adaptin (AP1G1) Mouse Monoclonal Antibody [Clone ID: IMD-113]
CAT#: AM20688PU-N
gamma Adaptin (AP1G1) mouse monoclonal antibody, clone IMD-113, Purified
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Specifications
Product Data | |
Clone Name | IMD-113 |
Applications | WB |
Recommended Dilution | Western Blot: 2 - 4 μg/ml. |
Reactivities | Human, Rat |
Host | Mouse |
Isotype | IgG2b |
Clonality | Monoclonal |
Immunogen | AP-1 adaptor from bovine brain. |
Specificity | This antibody reacts to AP1 complex subunit gamma-1. |
Formulation | 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative. State: Purified State: Lyphilized purified Ig fraction |
Reconstitution Method | Restore with 1.2% sodium acetate or neutral PBS |
Concentration | lot specific |
Purification | Affinity chromatography |
Storage | Prior to reconstitution store at -20°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | Homo sapiens adaptor related protein complex 1 gamma 1 subunit (AP1G1), transcript variant 2 |
Database Link | |
Background | Adaptins are important components of heterotetrameric adaptor complexes (APs) whose role is to promote the formation of clathrin-coated pits and vesicles. The AP-1 adaptor, localized at the trans-Golgi network, is composed of 2 approximately 100-kD subunits, beta-prime-adaptin and gamma-adaptin. The predicted 825-amino acid protein shares 99% identity with mouse gamma-adaptin. Northern blot analysis revealed that gamma-adaptin was expressed as a 7.5-kb transcript in all human tissues tested. Human gamma-adaptin gene (ADTG) is assigned to 16q23. |
Synonyms | ADTG, CLAPG1, gamma 1 Adaptin, gamma Adaptin |
Reference Data | |
Protein Pathways | Lysosome |
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