ABCA1 (1800-2260) Mouse Monoclonal Antibody [Clone ID: AB1.G6]

CAT#: AM20835PU-N

ABCA1 (1800-2260) mouse monoclonal antibody, clone AB1.G6, Aff - Purified

Specifications

Product Data

• Clone Name: AB1.G6
• Applications: ELISA, IHC, IP, WB
• Recommended Dilution: ELISA: 3-6 µg/ml.
  Western Blot: 1/1000–1/2000.
  Immunoprecipitation.
  Immunohistochemistry on Paraffin Sections.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Peptides amino acids 1800-2260
• Specificity: This antibody recognizes ABCA1 (1800-2260).
• Formulation: PBS, pH 7.4 with 0.05% Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens ATP binding cassette subfamily A member 1 (ABCA1)
• Database Link:
  Entrez Gene 19 Human
• Background: Mutations in the ABCA1 gene (ATP-binding cassette transporter 1) are associated with Tangier disease (TD). TD is an autosomal recessive disorder results from an absence of plasma HDL, cholesterol ester depositing in the reticulo-endothelial system and disorders in cellular lipid trafficking. It is expressed on the plasma membrane and the Golgi complex, and is regulated by cholesterol flux. Regulation of the cholesterol flux between HDL and macrophages is competitive between ABCA1 and SR-BI.
• Synonyms: ABC1, ABC-1, CERP

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: ABC transporters