Interferon gamma (IFNG) Mouse Monoclonal Antibody [Clone ID: 3F1E3]

CAT#: AM20853PU-N

Interferon gamma (IFNG) mouse monoclonal antibody, clone 3F1E3, Aff - Purified

Product Images

Western Blot analysis using anti-Human IFNG Monoclonal Antibody against Truncated IFNG Recombinant protein.

Specifications

Product Data

• Clone Name: 3F1E3
• Applications: ELISA, WB
• Recommended Dilution: ELISA.
  Western blot: 1/500-1/1,000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Ni-NTA purified recombinant human IFN-γ expressed in E. Coli strain BL21 (DE3)
• Specificity: This antibody recognizes Recombinant IFNG / Interferon gamma Western Blot and ELISA. Other species not tested.
• Formulation: State: Aff - Purified
  State: Liquid purified IgG fraction
• Purification: Affinity Chromatography on Protein A
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens interferon, gamma (IFNG)
• Database Link:
  Entrez Gene 3458 Human
• Background: Interferon-γ (IFN-γ) is a pro-inflammatory cytokine that is central in host resistance to infection. It is mainly produced by natural killer cells and CD4+ and CD8+ T cells, its receptors are found on nearly all cells, where it activates diverse responses that enable potential host cells to prevent invasive infection by bacteria, parasites and viruses. Takayanagi et al. (2000) demonstrated that IFN-γ strongly suppresses osteoclastogenesis by interfering with the RANKL (602642)-RANK (603499) signaling pathway. Tsubota et al. (1999) reported that this upregulation in Sjogren syndrome patients may be controlled by interferon-gamma through the activation of transcription factor NFKB.
• Synonyms: IFN-gamma, gamma IFN

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Allograft rejection, Cytokine-cytokine receptor interaction, Graft-versus-host disease, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity, Proteasome, Regulation of autophagy, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, Type I diabetes mellitus