Antithrombin III (SERPINC1) Mouse Monoclonal Antibody [Clone ID: n.a]

CAT#: AM20859PU-N

Antithrombin III (SERPINC1) mouse monoclonal antibody, clone n.a, Purified

Product Images

Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Clone Name: n.a
• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA.
  Immunohistochemistry on Paraffin Sections: 1/50.
  Western Blot: 1/1000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified Aantithrombin III protein purified from Human plasma
• Specificity: Recognizes Antithrombin-III (SERPINC1).
• Formulation: HEPES with 0.15M NaCl, 0.01% BSA, 0.03% Sodium Azide, and 50% Glycerol
  State: Purified
  State: Liquid purified Ig fraction
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens serpin peptidase inhibitor, clade C (antithrombin), member 1 (SERPINC1)
• Database Link:
  Entrez Gene 462 Human
• Background: Antithrombin III is a plasma protein synthesized in the liver and has molecular weight of 58kDa. Antithrombin III is a heparin-binding glycoprotein that acts as the major inhibitor of thrombin. Also it interferes with several plasma proteases, including kallikrein and factors IXa, Xa, XIa and XIIa, thereby playing a central role in regulating coagulation. It is also used as a therapeutic agent in patients with sepsis and disseminated intravascular coagulation. In addition, a number of recent studies have shown that antithrombin III has anti-inflammatory properties, which are independent of its effects on coagulation.
• Synonyms: AT3, Serpin C1, ATIII

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Complement and coagulation cascades