FOXA1 (367-473) Mouse Monoclonal Antibody [Clone ID: 4F6]

CAT#: AM20900PU-N

FOXA1 (367-473) mouse monoclonal antibody, clone 4F6, Purified

Product Images

FOXA1 monoclonal antibody clone 4F6 Western Blot analysis of FOXA1 expression in A-431.

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  FOXA1 monoclonal antibody clone 4F6 Western Blot analysis of FOXA1 expression in HepG2.

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  Detection limit for recombinant GST tagged FOXA1 is approximately 0.03 ng/ml as a capture antibody.

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  Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Immunofluorescence of monoclonal antibody to FOXA1 on A-431 cell (antibody concentration 10 ug/ml).

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Specifications

Product Data

• Clone Name: 4F6
• Applications: ELISA, IF, IHC, WB
• Recommended Dilution: ELISA.
  Immunofluorescence: 10 µg/ml.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Recombinant protein, FOXA1 (NP_004487, 367 a.a. ~ 473 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Specificity: This antibody reacts to Forkhead Box A1 (FOXA1).
• Formulation: PBS, pH 7.4
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A Chromatography
• Storage: Store the antibody at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens forkhead box A1 (FOXA1)
• Database Link:
  Entrez Gene 3169 Human
• Background: Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity).
• Synonyms: Forkhead box protein A1, HNF3A, HNF-3A, HNF-3-alpha, TCF-3A

Reference Data

• Protein Families: ES Cell Differentiation/IPS, Transcription Factors