PAX7 (411-521) Mouse Monoclonal Antibody [Clone ID: 1E12]

CAT#: AM20925PU-N

PAX7 (411-521) mouse monoclonal antibody, clone 1E12, Purified

Product Images

PAX7 monoclonal antibody clone 1E12 Western Blot analysis of PAX7 expression in NIH/3T3.

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  Detection limit for recombinant GST tagged PAX7 is approximately 3 ng/ml as a capture antibody.

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  Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Clone Name: 1E12
• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot.
• Reactivities: Human, Mouse
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: PAX7 (NP_002575, 411 a.a. ~ 521 a.a) partial recombinant protein with GST tag.
• Specificity: This antibody reacts to Paired Box Containing Transcription Factor Pax7 (PAX7) at aa 411-521.
• Formulation: PBS, pH 7.4
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A Chromatography
• Storage: Upon receipt, store the antibody (in aliquotes) at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens paired box 7 (PAX7), transcript variant 3
• Database Link:
  Entrez Gene 18509 MouseEntrez Gene 5081 Human
• Background: This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box gene 7 is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Alternative splicing in this gene has produced two known products but the biological significance of the variants is unknown.
• Synonyms: Pax-7, HUP1

Reference Data

• Protein Families: Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Transcription Factors