cGKI (PRKG1) Mouse Monoclonal Antibody [Clone ID: 2B3]

CAT#: AM20929PU-N

cGKI (PRKG1) mouse monoclonal antibody, clone 2B3, Purified

Product Images

Detection limit for recombinant GST tagged PRKG1 is approximately 0.1 ng/ml as a capture antibody

• 

  Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Clone Name: 2B3
• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot: 1/500 - 1/1000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant protein, PRKG1 (NP_006249, 73 a.a. ~ 171 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Specificity: This antibody reacts to CGMP-Dependent Protein Kinase Type I (PRKG1).
• Formulation: PBS, pH 7.2
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A Chromatography
• Storage: Store the antibody at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens protein kinase, cGMP-dependent, type I (PRKG1), transcript variant 1
• Database Link:
  Entrez Gene 5592 Human
• Background: PRKG1, a cGMP type protein kinase, is associated with physiologic processes such as relaxation of vascular smooth muscle and inhibition of platelet aggregation. PRKG1 is activated by binding to cGMP. At least two mRNA variants have been reported - the first two of 19 exons are used alternatively and encode the alpha and beta isoform specific sequences.
• Synonyms: PRKG1, PRKGR1A, PRKGR1B, CKG1A, CKG1B, PKG, PGK, cGKI-alpha

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Gap junction, Long-term depression, Olfactory transduction, Vascular smooth muscle contraction