RRM2 Mouse Monoclonal Antibody [Clone ID: 1E1]

CAT#: AM20936PU-N

RRM2 mouse monoclonal antibody, clone 1E1, Purified

Product Images

RRM2 monoclonal antibody clone 1E1. Western Blot analysis of RRM2 expression in HepG2.

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  Detection limit for recombinant GST tagged RRM2 is approximately 0.03 ng/ml as a capture antibody.

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  Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Immunofluorescence of monoclonal antibody to RRM2 on HeLa cell (antibody concentration 10 ug/ml).

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Specifications

Product Data

• Clone Name: 1E1
• Applications: ELISA, IF, IHC, WB
• Recommended Dilution: ELISA.
  Immunofluorescence: 10 µg/ml.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant protein, RRM2 (NP_001025, 1 a.a. ~ 111 a.a) partial recombinant protein with GST tag.
• Specificity: This antibody recognizes Ribonucleoside-diphosphate Reductase M2 Chain (RRM2).
• Formulation: PBS, pH 7.2
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A Chromatography
• Storage: Store the antibody (in aliquots) at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens ribonucleotide reductase regulatory subunit M2 (RRM2), transcript variant 2
• Database Link:
  Entrez Gene 6241 Human
• Background: Ribonucleotide reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. It is composed of 2 non-identical subunits, proteins M1 and M2. Synthesis of M2 is regulated in a cell-cycle dependent fashion.
• Synonyms: Ribonucleotide reductase small subunit, Ribonucleotide reductase small chain

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Glutathione metabolism, Metabolic pathways, p53 signaling pathway, Purine metabolism, Pyrimidine metabolism