Frataxin (FXN) Mouse Monoclonal Antibody [Clone ID: 2FRA-1G2]

CAT#: AM21056PU-N

Frataxin (FXN) mouse monoclonal antibody, clone 2FRA-1G2, Aff - Purified

Product Images

Frataxin antibody staining of Paraffin Human Brain Cortex Section (Clone 2FRA-1G2 )

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  Frataxin antibody staining of Paraffin Swine Brain Cortex Section (Clone 2FRA-1G2 )

Specifications

Product Data

• Clone Name: 2FRA-1G2
• Applications: IHC
• Recommended Dilution: Immunohistochemistry on Frozen Sections: Not tested.
  Immunohistochemistry on Paraffin Sections: 20 µg/ml (1/10). Proteinase K pretreatment for antigen retrieval recommended.
  Suggested Positive Control: Swine brain cortex.
• Reactivities: Human, Porcine
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: TrpE-Frataxin full length.
• Specificity: This Monoclonal antibody Clone 2FRA-1G2 recognizes Human Frataxin. Frataxin is localized to the mitochondrion.
  Antigen Distribution: The antigen has been described in the heart, peripheral blood lymphocytes and dermal fibroblasts.
• Formulation: Stock solution contains PBS, pH 7.2 with 5mg/ml BSA as stabilizer and 0.01% Kathon as a preservative
  State: Aff - Purified
  State: Lyophilized purified IgG fraction
• Reconstitution Method: Restore by adding 0.5 ml distilled water
• Concentration: 0.5 mg/ml (after reconstitution)
• Purification: Affinity Chromatography
• Storage:

  Prior to reconstitution store at 2-8°C.
  Following reconstitution store undiluted at 2-8°C for one month
  or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens frataxin (FXN), transcript variant 1
• Database Link:
  Entrez Gene 2395 Human
• Background: The function of frataxin is not entirely clear, but it seems to be involved in assembly of iron-sulfur clusters. It has been proposed to act as either an iron chaperone or an iron storage protein.
• Synonyms: Frataxin mitochondrial, FRDA, Friedreich ataxia protein

Reference Data

• Protein Families: Druggable Genome