CD36 Mouse Monoclonal Antibody [Clone ID: CB38 (NL07)]

CAT#: AM26005PU-N

CD36 mouse monoclonal antibody, clone CB38 (NL07), Purified

Specifications

Product Data

• Clone Name: CB38 (NL07)
• Applications: FC
• Recommended Dilution: Flow cytometry: 1 μg/ml.
• Reactivities: Human
• Host: Mouse
• Isotype: IgM
• Clonality: Monoclonal
• Immunogen: Living human myeloid cells
• Specificity: This antibody recognizes CD36 (GPIIIb), a 85-113 kDa integral membrane glycoprotein expressed on platelets, macrophages, endothelial cells, early erythroid cells and megakaryocytes.
• Formulation: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
  State: Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Precipitation methods (> 95% pure by SDS-PAGE)
• Storage: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens CD36 molecule (CD36), transcript variant 3
• Database Link:
  Entrez Gene 948 Human
• Background: CD36 (fatty acid translocase, FAT) is an 85-113 kDa ditopic glycosylated protein that belongs to the class B family of scavenger receptors. CD36 is expressed by most resting marginal zone B cells but not by follicular and B1 B cells, and it is rapidly induced on Follicular B cells in vitro upon TLR and CD40 stimulation. CD36 does not affect the development of B cells, but modulates both primary and secondary antibody response. Similarly to glucose transporter GLUT4, CD36 is translocated from intracellular pools to the plasma membrane following cell stimulation by insulin. In mouse, CD36 is responsible for gustatory perception of long-chain fatty acids.
• Synonyms: Glycoprotein IIIb, PAS IV, PAS-4, Thrombospondin receptor, GP3B, GP4

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Adipocytokine signaling pathway, ECM-receptor interaction, Hematopoietic cell lineage, PPAR signaling pathway