Prion protein PrP (PRNP) Mouse Monoclonal Antibody [Clone ID: EM-20]

CAT#: AM26026PU-N

Prion protein PrP (PRNP) mouse monoclonal antibody, clone EM-20, Aff - Purified


USD 320.00

2 Weeks*

Size
    • 100 ug

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Specifications

Product Data
Clone Name EM-20
Applications IHC, WB
Recommended Dilution Western blot: 0.5 μg/ml (Non-reducing conditions are essential).
This clone has been described to work in Immunohistochemistry on Paraffin Sections (10 µg/ml).
Reactivities Human
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Recombinant human prion protein
Specificity The Mouse monoclonal antibody EM-20 recognizes Human prion protein (PrP). Diglycosylated form of PrP has ~40 kDa, monoglycosylated form ~30 kDa, and nonglycosylated form ~19-21 kDa.
This antibody is suitable for discrimination between normal cellular prion protein (PrPc) and its conformationally changed form (PrPSc) prion protein.
Formulation PBS, pH~7.4
State: Aff - Purified
State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE)
Preservative: 15mM Sodium Azide
Concentration lot specific
Purification Affinity Chromatography on Protein A
Conjugation Unconjugated
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens prion protein (PRNP), transcript variant 1
Background The mouse monoclonal antibody EM-20 recognizes human prion protein (PrP). Diglycosylated form of PrP has ~ 40 kDa, monoglycosylated form ~ 30 kDa, and nonglycosylated form ~ 19-21 kDa. This antibody is suitable for discrimination between normal cellular prion protein (PrPc) and its conformationally changed form (PrPSc) prion protein.
Synonyms Major prion protein, PrP27-30, PrP33-35C, ASCR, PRNP, PRIP
Reference Data
Protein Families ES Cell Differentiation/IPS, Stem cell - Pluripotency, Transmembrane
Protein Pathways Prion diseases

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.