TAPA1 (CD81) Mouse Monoclonal Antibody [Clone ID: M38]
Specifications
Product Data | |
Clone Name | M38 |
Applications | FC |
Recommended Dilution | Flow Cytometry analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. |
Reactivities | Feline, Human, Rabbit |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | MOLT-4 (human T-ALL cell line) |
Specificity | This antibody reacts with CD81, a 25 kDa member of the tetraspanin family, expressed on majority of cells. |
Formulation | Phosphate buffered saline (PBS) Label: APC State: Liquid purified Ig fraction Preservative: 15 mM sodium azide Label: Conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary. |
Conjugation | APC |
Storage | Store the antibody undiluted at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. |
Stability | Shelf life: one year from despatch. |
Database Link | |
Background | CD81 (TAPA-1), a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T and other cells – e.g. in muscles CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus. |
Synonyms | S5.7; TAPA-1; TAPA1; Tetraspanin-28; Tspan-28; TSPAN28 |
Reference Data |
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