CD41 (ITGA2B) Mouse Monoclonal Antibody [Clone ID: 96.2C1]

CAT#: AM26055PU-N

CD41 (ITGA2B) mouse monoclonal antibody, clone 96.2C1, Aff - Purified

Product Images

Immunohistochemistry on frozen sections: Staining with AM26055PU-N on human placenta

Specifications

Product Data

• Clone Name: 96.2C1
• Applications: FC, IHC
• Recommended Dilution: Immunohistochemistry on frozen sections: 1 μg/ml (1:400).
  Has been described to work in FACS.
  Suggested positive control: Human placenta.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Specificity: This antibody recognizes the CD41 antigen of the CD41/61 complex expressed on platelets and megakaryocytes.
• Formulation: Stock solution contains 0.4mg/ml IgG, phosphate buffered saline pH 7.2 (PBS), 5mg/ml bovine serum albumin (BSA), and 0.09% sodium azide as a preservative
  State: Aff - Purified
  State: Lyophilized Ig fraction
• Reconstitution Method: Reconstitute by adding 0.5ml distilled water.
• Purification: Affinity chromatography
• Storage: Prior to reconstitution store at 2-8°C. Following reconstitution store (in aliquots) at -20°C. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens integrin subunit alpha 2b (ITGA2B)
• Database Link:
  Entrez Gene 3674 Human
• Background: The CD41/CD61 complex, also known as platelet glycoprotein (GP) IIb/IIIa, or integrin αIIbβ3, mediates platelet aggregation by serving as the receptor for fibrinogen and von Willebrand factor.
• Synonyms: Integrin alpha-IIb, GP2B, ITGAB, GPalpha IIb
• Note: Antigen, epitope:
  The antigen is CD41, a 140kD glycoprotein. The epitope has
  not been further chracterized.
  Antigen distribution:
  Isolated cells: The antibody stains >90% of human peripheral blood platelets in flow cytometry.
  Tissue sections: platelets.

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Hypertrophic cardiomyopathy (HCM), Pathways in cancer, Regulation of actin cytoskeleton, Small cell lung cancer