Cr1l Mouse Monoclonal Antibody [Clone ID: 512]

CAT#: AM26059PU-N

Cr1l mouse monoclonal antibody, clone 512, Aff - Purified

Product Images

Immunohistochemistry on frozen sections: Staining of rat spleen with AM26059PU-N

Specifications

Product Data

• Clone Name: 512
• Applications: FC, IHC
• Recommended Dilution: Immunohistochemistry on frozen sections: 0.1 μg/ml (1:4000).
  Does not react on routinely processed paraffin sections.
  Has been reported to work in FACS.
  Suggested positive control: rat spleen.
• Reactivities: Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Erythrocytes from a C3 mutated rat
• Specificity: This antibody detects Crry.
  The antigen is found on numerous cells in blood and various
  tissues.
• Formulation: Stock solution contains 0.4 mg/ml IgG, phosphate buffered saline pH 7.2 (PBS), 5mg/ml bovine serum albumin (BSA) as a stabilizer and 0.09% sodium azide as a preservative.
  State: Aff - Purified
  State: Liquiphilized Ig fraction
• Reconstitution Method: Reconstitute by adding 0.5 ml distilled water.
• Purification: Affinity chromatography
• Storage: Prior to reconstitution store at 2-8°C. Following reconstitution store (in aliquots) at -20°C. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Rattus norvegicus complement C3b/C4b receptor 1 like (Cr1l), transcript variant 3
• Database Link:
  Entrez Gene 54243 Rat
• Background: Crry is a cofactor for complement factor I.
  Crry seems to act as a costimulatory factor for T-cells and is expressed on different tissues, particularly also on thymocytes and non-lymphoid cells in the thymus. Crry may play an important role in the early embryonic development by maintaining fetomaternal tolerance.
  Two forms of Crry exist, containing six or seven extracellular short consensus repeats (SCRs), respectively, plus a transmembrane and a cytoplasmic domain. The molecular weights of the native glycoproteins are approximately 55 and 65kDa, respectively.
• Synonyms: Antigen 5I2