HLA Class II DR Mouse Monoclonal Antibody [Clone ID: EDU-1]

CAT#: AM26129BT-N

HLA Class II DR mouse monoclonal antibody, clone EDU-1, Biotin

Product Images

Human tonsil frozen section stained with AM26129BT-N (Clone EDU-1)

Specifications

Product Data

• Clone Name: EDU-1
• Applications: FC, IHC
• Recommended Dilution: Immunohistochemistry on Frozen Sections: 0.1 µg/ml (1/2000).
  Suggested Positive Control: Human tonsil.
  Has been described to work in FACS.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Specificity: This antibody recognizes HLA DR antigen.
• Formulation: Phosphate buffered saline pH 7.2 (PBS)
  Label: Biotin
  State: Lyophilized purified Ig fraction
  Stabilizer: 5 mg/ml BSA
  Preservative: 0.05 % (v/v) Kathon CG
• Reconstitution Method: Restore by adding 0.5ml distilled water.
• Concentration: 0.2 mg/ml (after reconstitution)
• Purification: Affinity Chromatography
• Conjugation: Biotin
• Storage: Store lyophilized at 2-8°C for 6 months or at -20°C long term.
  After reconstitution store the antibody undiluted at 2-8°C for one month
  or (in aliquots) at -20°C long term.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Background:

  HLA DR antigen is an HLA class II antigen with homology to murine H-2E. HLA-DR is an αβ heterodimer. The N-terminal domain of the mature protein forms an alpha-helix that constitutes the exposed part of the binding groove, the C-terminal cytoplasmic region interacts with the other chain forming a beta-sheet under the binding groove spanning to the cell membrane.

• Synonyms: HLA-DR, HLA class II histocompatibility antigen DR, MHC class II antigen DR
• Note: Antigen distribution:
  Isolated cells: Antigen presenting cells (macrophages, B-cells and dendritic cells) are the cells in which DR are typically found.