HLA Class II DR Mouse Monoclonal Antibody [Clone ID: EDU-1]

CAT#: AM26129PU-N

HLA Class II DR mouse monoclonal antibody, clone EDU-1, Aff - Purified

Product Images

Immunohistochemistry on frozen sections: Staining with AM26129PU-N on human tonsil.

Specifications

Product Data

• Clone Name: EDU-1
• Applications: FC, IHC
• Recommended Dilution: Immunohistochemistry on frozen sections: ≤0.1μg/ml (1:2000).
  Has been described to work in FACS.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Specificity: This antibody recognizes the HLA DR antigen, an HLA class II antigen with homology to murine H-2E.
• Formulation: Phosphate buffered saline pH 7.2 (PBS), 5mg/ml bovine serum albumin (BSA), and 0.09% sodium azide as a preservative.
  State: Aff - Purified
  State: Lyophilized Ig fraction
• Reconstitution Method: Reconstitute by adding 0.5ml distilled water.
• Purification: Affinity chromatography
• Storage: Prior to reconstitution store at 2-8°C. Following reconstitution store (in aliquots) at -20°C. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Background: HLA-DR is an αβ heterodimer. The N-terminal domain of the mature protein forms an alpha-helix that constitutes the exposed part of the binding groove, the C-terminal cytoplasmic region interacts with the other chain forming a beta-sheet under the binding groove spanning to the cell membrane.
• Synonyms: HLA-DR, HLA class II histocompatibility antigen DR, MHC class II antigen DR
• Note: Antigen distribution:
  Isolated cells: Antigen presenting cells (macrophages, Bcells and dendritic cells) are the cells in which DR are typically found.