LY75 (LY75-CD302) Mouse Monoclonal Antibody [Clone ID: HD30]

CAT#: AM26139RP-N

LY75 (LY75-CD302) mouse monoclonal antibody, clone HD30, PE


USD 300.00

2 Weeks*

Size
    • 100 Tests

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Specifications

Product Data
Clone Name HD30
Applications FC
Recommended Dilution Flow Cytometry analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 10e6 cells in a suspension. 
The content of a vial (1 ml) is sufficient for 100 tests.
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Recombinant Fc-tagged human CD205
Specificity This antibody detects CD205.
Formulation Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent
Label: PE
State: Liquid purified Ig fraction
Label: Conjugated with R-Phycoerythrin under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use
Conjugation PE
Gene Name Homo sapiens LY75-CD302 readthrough (LY75-CD302), transcript variant 1
Background CD205, also known as DEC-205, is an endocytic receptor of macrophage mannose receptor family. This 205 kDa C-type lectin transmembrane protein mediates adsorptive uptake and its intracellular domain contains coated pit localization sequence and distal acidic motif, which is required for recycling beyond early endosomes through deeper MHC II+ late endosomes and lysosomes. This unique pathway of receptor-mediated uptake proves to be necessary for presentation of antigenic peptides at low doses of ligand. CD205 is responsible for uptake and processing of captured antigens for dendritic cells.
Synonyms LY75, CLEC13B, DEC205, gp200-MR6
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.