CD73 (NT5E) Mouse Monoclonal Antibody [Clone ID: AD2]

CAT#: AM26144FC-N

CD73 (NT5E) mouse monoclonal antibody, clone AD2, FITC


USD 270.00

2 Weeks*

Size
    • 100 Tests

Product Images

Specifications

Product Data
Clone Name AD2
Applications FC
Recommended Dilution Flow Cytometry analysis of Human blood cells using 4 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Specificity This antibody AD2 recognizes CD73, a 70 kDa GPI-anchored 5´-nucleotidase expressed predominantly on T and B cell subsets, follicular dendritic cells and endothelial cells.
Formulation PBS
Label: FITC
State: Liquid purified Ig fraction
Preservative: 15 mM Sodium Azide
Label: Conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use.
Conjugation FITC
Storage Store undiluted at 2-8°C.
DO NOT FREEZE!
This products is photosensitive and should be protected from light.
Stability Shelf life: one year from despatch.
Gene Name 5'-nucleotidase ecto
Background CD73 (ecto-5´-nucleotidase) is a 70 kDa glycoprotein anchored to the extracellular leaflet of the plasma membrane by GPI. This ecto-enzyme catalyzes dephosphorylation of AMP to adenosine. CD73 is expressed in various types of cells, such as epithelial, muscle, and endothelial cells, neutrophils, lymphocytes and fibroblasts. Inflammatory mediators support CD73 expression and its enzymatic activity, leading to the release of adenosine, which modulates inflammation through adenosine receptors. CD73 is expressed in a variety of lymphomas and leukemias, including ALL and CLL, whereas immunodeficient patients usually express low levels of this protein.
Synonyms NT5, NTE, NT5E
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.