Myeloperoxidase (MPO) Mouse Monoclonal Antibody [Clone ID: 2D4]

CAT#: AM26163FC-N

Myeloperoxidase (MPO) mouse monoclonal antibody, clone 2D4, FITC


USD 600.00

2 Weeks*

Size
    • 100 ug

Product Images

Specifications

Product Data
Clone Name 2D4
Applications ELISA, IF, IHC
Recommended Dilution Immunoassay.
Immunoflourescence.
Flow cytometry (starting working dilution is 1:50).
Immunohistochemistry on frozen sections (starting working dilution is 1:50).
The antibody is not useful for Western blotting and immunohistology on paraffin embedded sections.
Reactivities Mouse, Rat
Host Mouse
Isotype IgG1
Clonality Monoclonal
Specificity This antibody detects myeloperoxidase (MPO).
Formulation PBS
Label: FITC
State: Liquid 0.2 µm filtered Ig fraction
Stabilizer: 1% bovine serum albumin
Preservative: 0.02% sodium azide
Purification Protein G
Conjugation FITC
Storage

Store at 2 - 8 °C.

Stability Shelf life: one year from despatch.

Gene Name myeloperoxidase
Background MPO is a glycoprotein with an alpha2beta2 heteromultimer expressed in all cells of the myeloid linage. MPO is abundantly present in azurophilic granules of polymorphonuclear neutrophils. It is an important enzyme used during phagocytic lysis of engulfed foreign particles which takes part in the defense of the organism through production of hypochlorous acid (HOCl), a potent oxidant. MPO is rapidly released by activated polymorphonuclear neutrophils. Involvement of MPO has been described in numerous diseases such as atherosclerosis, lung cancer, Alzheimer's disease and multiple sclerosis. Autoimmune antibodies to MPO are involved in Wegeners disease. Since the discovery of MPO deficiency, initially regarded as rare and restricted to patients suffering from severe infections, MPO has more attracted clinical attention. In experimental studies antibodies to MPO can be used for various purposes ranging from flow cytometric analysis to detection of polymorphonuclear neutrophils in tissue sections.
Synonyms MPO
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.