IL1 Receptor II (IL1R2) Mouse Monoclonal Antibody [Clone ID: 8.5]

CAT#: AM26271FC-N

IL1 Receptor II (IL1R2) mouse monoclonal antibody, clone 8.5, FITC


USD 445.00

2 Weeks*

Size
    • 100 ug

Product Images

Specifications

Product Data
Clone Name 8.5
Applications ELISA, WB
Recommended Dilution Flow cytometry: The typical starting working dilution is 1:50.
Immunoassay.
Western blot: The typical starting working dilution is 1:50.
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Specificity
The antibody reacts specificly with IL-1RII.
Formulation PBS
Label: FITC
State: Liquid 0.2 µm filtered Ig fraction
Stabilizer: 1% bovine serum albumin
Preservative: containing 0.02% sodium azide
Concentration 0.1 mg/ml
Purification Protein G
Conjugation FITC
Gene Name interleukin 1 receptor type 2
Background The IL-1 system includes two agonists (IL-1alpha and IL-1beta), converting enzymes, antagonists, two receptors (IL-1RI and IL-1RII) and the IL-1 receptor accessory protein. The IL-1RII is part of the antagonistic IL-1 mechanism. It is also known as decoy receptor and is a non signaling molecule which functions by capturing IL-1 and preventing it from interacting with the signalling IL-1RI. The decoy IL-1RII can after binding to IL-1 also recruit the IL-1 receptor accessory protein and thus inhibit by coreceptor competition. Further a soluble form of IL-1RII exists which is shed, a process in which matrix metalloproteases have been found to play a role, by various cells including monocytes, polymorphonuclear cells, B cells and fibroblasts.
Synonyms Interleukin-1 receptor type II, IL-1R-2, IL-1R-beta, CDw121b, IL1RB
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.