TNFRSF1B Mouse Monoclonal Antibody [Clone ID: MR2-1]
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Specifications
Product Data | |
Clone Name | MR2-1 |
Applications | ELISA, FC, FN, IHC, IP, WB |
Recommended Dilution | Immunohistochemistry on frozen sections: The typical starting working dilution is 1:10. Positive control: Human lymphnodes. Flow cytometry: The typical starting working dilution is 1:10. Positive control: PHA activated T cells. Functional assays. Immunoassays. Immunoprecipitation. Western blot: The typical starting working dilution is 1:10. The monoclonal antibody MR2-1 is an agonistic antibody (after cross-linking) and receptor modulating antibody. The reactivity of the antibody MR2-1 with cell-bound TNF-Receptor is minimally inhibited by high concentrations of TNF-alpha. |
Reactivities | Human, Monkey |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Specificity | The antibody MR2-1 reacts with the extra-cellular part of the TNF-RII. It also reacts with the soluble receptor. |
Formulation | PBS State: Purified State: Liquid 0.2 µm filtered Ig fraction Stabilizer: 0.1% bovine serum albumin |
Concentration | lot specific |
Purification | Protein G |
Storage | Store at 2 - 8 °C. |
Stability | Shelf life: one year from despatch. |
Gene Name | tumor necrosis factor receptor superfamily member 1B |
Database Link | |
Background | TNF-RII is present on most cell types and is considered to play a prominent role in cell stimulation by TNF-alpha. TNF-RII molecule is shown to be responsible for stimulation of activated T-lymphocytes by TNF-alpha. |
Synonyms | Tumor necrosis factor receptor 2, p80 TNF-alpha receptor, TNFRSF1B, TNFBR, TNF-R2 |
Note | |
Reference Data |
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