TNFRSF1B Mouse Monoclonal Antibody [Clone ID: MR2-1]

CAT#: AM26300PU-N

TNFRSF1B mouse monoclonal antibody, clone MR2-1, Purified

Specifications

Product Data

• Clone Name: MR2-1
• Applications: ELISA, FC, FN, IHC, IP, WB
• Recommended Dilution: Immunohistochemistry on frozen sections: The typical starting working dilution is 1:10. Positive control: Human lymphnodes.
  Flow cytometry: The typical starting working dilution is 1:10. Positive control: PHA activated T cells.
  Functional assays.
  Immunoassays.
  Immunoprecipitation.
  Western blot: The typical starting working dilution is 1:10.
  The monoclonal antibody MR2-1 is an agonistic antibody (after cross-linking) and receptor modulating antibody.
  The reactivity of the antibody MR2-1 with cell-bound TNF-Receptor is minimally inhibited by high concentrations of TNF-alpha.
• Reactivities: Human, Monkey
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Specificity:

  The antibody MR2-1 reacts with the extra-cellular part of the TNF-RII. It also reacts with the soluble receptor.

• Formulation: PBS
  State: Purified
  State: Liquid 0.2 µm filtered Ig fraction
  Stabilizer: 0.1% bovine serum albumin
• Concentration: lot specific
• Purification: Protein G
• Storage:

  Store at 2 - 8 °C.
  

• Stability: Shelf life: one year from despatch.

• Gene Name: tumor necrosis factor receptor superfamily member 1B
• Database Link:
  Entrez Gene 7133 Human
• Background: TNF-RII is present on most cell types and is considered to play a prominent role in cell stimulation by TNF-alpha. TNF-RII molecule is shown to be responsible for stimulation of activated T-lymphocytes by TNF-alpha.
• Synonyms: Tumor necrosis factor receptor 2, p80 TNF-alpha receptor, TNFRSF1B, TNFBR, TNF-R2
• Note: