IL6 Mouse Monoclonal Antibody [Clone ID: 8E10]

CAT#: AM26384PU-L

IL6 mouse monoclonal antibody, clone 8E10, Purified


USD 540.00

2 Weeks*

Size
    • 500 ug

Product Images

Specifications

Product Data
Clone Name 8E10
Applications ELISA, WB
Recommended Dilution ELISA. 
Western Blot.
Reactivities Human
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Purified recombinant human IL-6
Specificity The antibody is reactive with recombinant human IL-6.  Reactivity with natural antigen has not been evaluated.
Formulation 0.01M PBS, pH 7.0
State: Purified
State: Lyophilized Ig fraction
Reconstitution Method Double distillated water is recommended to reconstitute the antibody.
Purification Protein G affinity purified
Conjugation Unconjugated
Storage Store lyophilized at 2-8°C for 6 months or at -20°C long term.
After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name interleukin 6
Background Interleukin 6 (IL6) is a multifunctional 24 kDa protein originally discovered in the medium of RNA stimulated fibroblastoid cells. It is upregulated by IL1, TNF, PDGF, IFN beta, TNF alpha, NGF, IL17 and downregulated by glucocorticoids IL4, TGF beta. IL6 appears to be directly involved in the responses that occur after infection and cellular injury, and it may prove to be as important as IL1 and TNF alpha in regulating the acute phase response. IL6 has also been implicated in regulating adipose mass. IL6 is reported to be produced by fibroblasts, activated T cells, activated monocytes or macrophages and endothelial cells. It acts upon a variety of cells including fibroblasts, myeloid progenitor cells, T cells, B cells and hepatocytes. In addition, IL6 appears to interact with IL2 in the proliferation of T lymphocytes. IL6 potentiates the proliferative effect of IL3 on multipotential hematopoietic progenitors.
Synonyms IL-6, Interferon beta-2, IFNB2, B-cell stimulatory factor 2, BSF-2, CDF
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.