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hnRNP A2B1 (HNRNPA2B1) Mouse Monoclonal Antibody [Clone ID: C20308]
CAT#: AM26527AF-N
hnRNP A2B1 (HNRNPA2B1) mouse monoclonal antibody, clone C20308, Azide Free
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Specifications
| Product Data | |
| Clone Name | C20308 |
| Applications | IF, WB |
| Recommended Dilution | Western blot: 10 μg/ml for chemiluminescence detection system. Immunocytochemistry: 10 μg/ml. |
| Reactivities | Human, Mouse |
| Host | Mouse |
| Isotype | IgM |
| Clonality | Monoclonal |
| Immunogen | Protein fraction extracted from the mitotic chromosome |
| Specificity | This antibody reacts with hnRNP-A2/B1. |
| Formulation | PBS containing 50% glycerol, pH 7.2. No preservative is contained. State: Azide Free State: Liquid purified Ig fraction |
| Concentration | lot specific |
| Storage | Upon receipt, store (in aliqouts) at -20 °C. Avoid repeated freezing and thawing. |
| Stability | Shelf life: One year from despatch. |
| Predicted Protein Size | 40 kDa |
| Database Link | |
| Background | The heterogeneous nuclear ribonucleoprotein-A2/B1 (hnRNP-A2/B1) was recently shown to be up-regulated in th e early stage of lung cancer. This protein plays an important role in biogenesis and transport of mRNA. Up-regulation of hnRNP usually precedes morphological differentiation and is considered a good biomarker in the early stages of cancer development. HnRNP-A2/B1 proteins were localized primarily in the nucleus, excluding the nucleolus, although the expression of A2 protein was weaker than that of B1 protein. hnRNP-A2/B1 proteins were apparently expressed in nonmalignant alveolar cells as well as cancer cells, although the expression in alveolar cells was weaker than that of cancer cells. |
| Synonyms | Heterogeneous nuclear ribonucleoproteins A2/B1, hnRNP A2 / hnRNP B1, HNRPA2B1 |
| Note | This product was originally produced by MBL International. |
| Reference Data | |
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