CD82 Mouse Monoclonal Antibody [Clone ID: C33]

CAT#: AM26701PU-N

CD82 mouse monoclonal antibody, clone C33, Aff - Purified


USD 240.00

2 Weeks*

Size
    • 100 ug

Product Images

Specifications

Product Data
Clone Name C33
Applications FC, FN, IF, IHC, IP, WB
Recommended Dilution

Flow Cytometry.
Immunoprecipitation
Western blot.
Immunohistochemistry on Paraffin Sections.
Immunocytochemistry.
Functional Application: In Human MOLT-4 T-cell line the antibody C33 inhibits syncytium formation induced by coculture with Human T-cell leukemia virus type 1 (HTLV-1)-positive Human T-cell lines.

Reactivities Human
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen C91/PL (Human HTLV-1+ T cell line)
Specificity The antibody reacts with CD82, a widely expressed cell surface protein of the tetraspanin family. CD82 is also found in endosome/lysosome compartments.
Formulation Phosphate buffered saline (PBS), approx. pH 7.4
State: Aff - Purified
State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE)
Preservative: 15 mM Sodium Azide
Concentration lot specific
Purification Protein-A Affinity Chromatography
Storage

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.

Stability Shelf life: one year from despatch.

Background CD82 (KAI1), a member of the tetraspanin family, forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules. These complexes influence adhesion, morphology, activation, proliferation and differentiation of B, T and other cells. CD82 regulates cytoskeleton rearrangement and may participate in the turnover of the tetraspanin complex members. Besides in the plasma membrane, CD82 is localized also in endosome/lysosome compartments. Tumour-suppressive roles of CD82 have been demonstrated.
Synonyms KAI1, SAR2, ST6, TSPAN27, C33 antigen, IA4, Kangai-1, Tetraspanin-27
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.