TUBGCP2 (2-194) Mouse Monoclonal Antibody [Clone ID: GCP2-01]
CAT#: AM26702PU-N
TUBGCP2 (2-194) mouse monoclonal antibody, clone GCP2-01, Aff - Purified
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Specifications
| Product Data | |
| Clone Name | GCP2-01 |
| Applications | IF, IHC, IP, WB |
| Recommended Dilution | Immunoprecipitation. |
| Reactivities | Human, Mouse, Porcine, Rat |
| Host | Mouse |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Immunogen | GST-fusion protein containing amino acids 2-194 of mouse GCP2 |
| Specificity | The antibody recognizes gamma-tubulin complex component 2 (GCP2), a 95-103 kDa protein. It recognizes also phosphorylated GCP2. |
| Formulation | Phosphate buffered saline (PBS), approx. pH 7.4 State: Aff - Purified State: Liquid Ig fraction Preservative: 15 mM sodium azide |
| Concentration | 1.0 mg/ml |
| Purification | Protein-A affinity chromatography (> 95% by SDS-PAGE) |
| Database Link | |
| Background | Gamma tubulin complex component 2 (GCP2) is 95-103 kDa protein which associates with two molecules of gamma tubulin and one molecule of gamma tubulin complex component 3 (GCP3), to form the gamma tubulin small complexes (gammaTuSCs). These complexes interact with GCP4, 5, and 6 to form the gamma tubulin ring complexes (gammaTuRCs), which are embedded in the microtubule organizing center matrix where they nucleate microtubules. The gammaTuRCs are also involved in the regulation of microtubule plus and minus end dynamics. Components of gamma tubulin complexes are highly conservative in eukaryotes. |
| Synonyms | GCP-2, GCP2, Spc97, Grip103 |
| Reference Data | |
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