HLA Class II DR Monoclonal Antibody [Clone ID: L243]

CAT#: AM26708LE-N

HLA Class II DR monoclonal antibody, clone L243, Low Endotoxin

Product Images

Surface staining of HLA-DR in human peripheral blood with anti-HLA-DR (L243) PerCP-Cy5.5.

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  Surface staining of HLA-DR in human peripheral blood with anti-HLA-DR (L243) APC-Cy7.

Specifications

Product Data

• Clone Name: L243
• Applications: FC, FN, IF, IHC, IP, WB
• Recommended Dilution: Flow cytometry.
  Immunoprecipitation.
  Western blot.
  Immunohistochemistry (paraffin sections).
  Immunohistochemistry (frozen sections).
  Immunocytochemistry.
  Functional Application: blocking.
• Reactivities: Canine, Human, Primate
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Human B lymphocytes
• Specificity: This antibody recognizes specifically HLA-DR molecules, both peptide-loaded and empty.
• Formulation: Azide free phosphate buffered saline (PBS), approx. pH 7.4; 0.2 μm filter sterilized
  State: Low Endotoxin
  State: Liquid Ig fraction
• Concentration: 1.0 mg/ml
• Purification: Protein-A affinity chromatography (> 95% pure by SDS-PAGE)
• Background: HLA-DR, a member of MHC class II glycoproteins, that bind intracellularly processed peptides and present them to the Th cells, is composed of 36 kDa alpha chain and 27 kDa beta chain, both anchored in the plasma membrane. Together with other MHC II molecules HLA-DR plays a central role in the immune system. It is expressed on antigen-presenting cells (dendritic cells, B lymphocytes, monocytes, macrophages).
• Synonyms: HLA-DR, HLA class II histocompatibility antigen DR, MHC class II antigen DR