HLA Class II DR Mouse Monoclonal Antibody [Clone ID: L243]

CAT#: AM26708PU-N

HLA Class II DR mouse monoclonal antibody, clone L243, Purified

Product Images

Surface staining of HLA-DR in human peripheral blood with anti-HLA-DR (L243) purified / GAM-APC.

Specifications

Product Data

• Clone Name: L243
• Applications: FC, FN, IF, IHC, IP, WB
• Recommended Dilution: Flow Cytometry.
  Immunoprecipitation.
  Western blot.
  Immunohistochemistry on Paraffin Sections.
  Immunohistochemistry on Frozen Sections.
  Immunocytochemistry.
  Functional Application: blocking.
• Reactivities: Canine, Human, Primate
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Human B lymphocytes
• Specificity: This antibody recognizes specifically HLA-DR molecules, both peptide-loaded and empty.
• Formulation: PBS, pH~7.4
  State: Purified
  State: Liquid purified IgG fraction (> 95% by SDS-PAGE)
  Preservative: 15 mM Sodium Azide
• Concentration: 1.0 mg/ml
• Purification: Affinity Chromatography on Protein A
• Background: HLA-DR, a member of MHC class II glycoproteins, that bind intracellularly processed peptides and present them to the Th cells, is composed of 36 kDa alpha chain and 27 kDa beta chain, both anchored in the plasma membrane. Together with other MHC II molecules HLA-DR plays a central role in the immune system. It is expressed on antigen-presenting cells (dendritic cells, B lymphocytes, monocytes, macrophages).
• Synonyms: HLA-DR, HLA class II histocompatibility antigen DR, MHC class II antigen DR