CD300E Mouse Monoclonal Antibody [Clone ID: UP-H2]

CAT#: AM26758AC-N

CD300E mouse monoclonal antibody, clone UP-H2, APC

Product Images

Surface staining of human peripheral blood with anti-human CD300e (UP-H2) APC.

Specifications

Product Data

• Clone Name: UP-H2
• Applications: FC
• Recommended Dilution: Flow Cytometry analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 10⁶ cells in a suspension.
  The content of a vial (1 ml) is sufficient for 100 tests.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: CD300e-HA-transfected cells
• Specificity: This antibody recognizes CD300e / IREM-2, a 32 kDa glycoprotein expressed by mature monocytes and peripheral blood myeloid dendritic cells.
• Formulation: Phosphate buffered saline (PBS)
  Label: APC
  State: Liquid purified Ig fraction
  Stabilizer: 0.2% (w/v) high-grade protease free BSA
  Preservative: 15 mM Sodium Azide
  Label: Conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use.
• Conjugation: APC
• Gene Name: CD300e molecule
• Database Link:
  Entrez Gene 342510 Human
• Background: CD300e / IREM-2 (immune receptor expressed by myeloid cells 2), also known as CLM2 or LMIR6, is a monomeric transmembrane glycoprotein with a single extracellular immunoglobulin-like domain. Intracellularly it associates with DAP-12, an ITAM-containing adaptor molecule. CD300e is expressed on mature monocytes and peripheral blood myeloid dendritic cells. Its crosslinking leads to release of pro-inflammatory cytokines, and increased expression of activation markers.
• Synonyms: CLM-2, CD300LE, CLM2, IREM2, CMRF35-A5