Fas Ligand (FASLG) Mouse Monoclonal Antibody [Clone ID: NOK-1]

CAT#: AM26762RP-N

Fas Ligand (FASLG) mouse monoclonal antibody, clone NOK-1, PE

Product Images

Surface staining of CD178 in CD178-transfected L5178Y cells with anti-CD178 (NOK-1) PE.

Specifications

Product Data

• Clone Name: NOK-1
• Applications: FC
• Recommended Dilution: Flow Cytometry analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 10⁶ cells in a suspension.
  The content of a vial (1 ml) is sufficient for 100 tests.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: L5178Y mouse T lymphoma cells expressing recombinant human CD178
• Specificity: This antibody recognizes CD178 / Fas-L, an approximately 40 kDa transmembrane glycoprotein expressed on neutrophils, monocytes, and activated T and NK cells.
• Formulation: Label: PE
  State: Liquid purified Ig fraction
  Label: Conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use.
• Conjugation: PE
• Storage: Prior to and following reconstitution store the antibody at 2-8°C.
  DO NOT FREEZE!
  This product is photosensitive and should be protected from light.
• Stability: Shelf life: one year from despatch.
• Database Link:
  Entrez Gene 356 Human
• Background: CD178 / Fas-L (Fas ligand, CD95L), a member of TNF family transmembrane glycoproteins, is responsible for induction of apoptosis in cells containing its receptor CD95 / Fas. The CD178-mediated apoptosis pathway has been implicated in peripheral tolerance, tissue pathology, and maintenance of the immune privileged sites. Defects in this interaction may be related to some cases of systemic lupus erythematosus (SLE). CD178 was also described as a co-stimulatory receptor for T-cell activation in mice in vivo.
• Synonyms: FASLG, APT1LG1, FASL, TNFSF6, CD95L protein, APTL