DDIT4L (2-98) Mouse Monoclonal Antibody [Clone ID: DDIT-03]

CAT#: AM26767PU-N

DDIT4L (2-98) mouse monoclonal antibody, clone DDIT-03, Purified

Product Images

Western blotting analysis of DDIT4L expression in HEK293-DDIT4L transfectants and HEK293 cells using mouse monoclonal antibody DDIT-03.

Specifications

Product Data

• Clone Name: DDIT-03
• Applications: FC, WB
• Recommended Dilution: Flow cytometry (intracellular staining).
  Western blot.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: N-terminal recombinant fragment of human DDIT4L (amino acids 2-98)
• Specificity: This antiobody recognizes DDIT4L / REDD2 protein, which belongs to stress-induced proteins involved in mediation of cell death.
• Formulation: Phosphate buffered saline (PBS)
  State: Purified
  State: Liquid Ig fraction
  Preservative: 15 mM sodium azide, approx. pH 7.4
• Concentration: 1.0 mg/ml (> 95% pure by SDS-PAGE)
• Purification: Protein-A affinity chromatography
• Database Link:
  Entrez Gene 115265 Human
• Background: DDIT4L (DNA-damage-inducible transcript 4-like), also known as REDD2 (regulated in development and DNA damage response 2) or RTP801L is a stress-inducted protein, which was shown to mediate monocyte cell death through a reduction in thioredoxin-1 expression, and is highly expressed in atherosclerotic lesions. Stimulation of DDIT4L expression in macrophages increases oxidized LDL-induced macrophage death.
• Synonyms: DNA-damage-inducible transcript 4-like protein, HIF-1 responsive protein, REDD2, REDD-2, RTP801L