DDIT4L (2-98) Mouse Monoclonal Antibody [Clone ID: DDIT-03]
Specifications
Product Data | |
Clone Name | DDIT-03 |
Applications | FC, WB |
Recommended Dilution | Flow cytometry. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | N-terminal recombinant fragment of human DDIT4L (amino acids 2-98) |
Specificity | This antibody recognizes DDIT4L / REDD2 protein, which belongs to stress-induced proteins involved in mediation of cell death. |
Formulation | Phosphate buffered saline (PBS) Label: PE State: Liquid purified Ig fraction Stabilizer: 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) Preservative: 15 mM sodium azide Label: Conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate was purified by size-exclusion chromatography. |
Concentration | 0.1 mg/ml |
Conjugation | PE |
Database Link | |
Background | DDIT4L (DNA-damage-inducible transcript 4-like), also known as REDD2 (regulated in development and DNA damage response 2) or RTP801L is a stress-inducted protein, which was shown to mediate monocyte cell death through a reduction in thioredoxin-1 expression, and is highly expressed in atherosclerotic lesions. Stimulation of DDIT4L expression in macrophages increases oxidized LDL-induced macrophage death. |
Synonyms | DNA-damage-inducible transcript 4-like protein, HIF-1 responsive protein, REDD2, REDD-2, RTP801L |
Reference Data |
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