TWEAKR (TNFRSF12A) Mouse Monoclonal Antibody [Clone ID: ITEM-4]

CAT#: AM26769RP-N

TWEAKR (TNFRSF12A) mouse monoclonal antibody, clone ITEM-4, PE


USD 300.00

2 Weeks*

Size
    • 100 ug

Product Images

Specifications

Product Data
Clone Name ITEM-4
Applications FC
Recommended Dilution Flow cytometry.
Reactivities Human, Mouse
Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Human CD266-transfected P815 cells
Specificity This antibody recognizes CD266 / TWEAK R, a TNFR superfamily receptor for CD255 / TWEAK, a TNF-like weak inducer of apoptosis.
Formulation Phosphate buffered saline (PBS)
Label: PE
State: Liquid purified Ig fraction
Stabilizer: 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA)
Preservative: 15 mM sodium azide
Label: Conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Conjugation PE
Background CD266 / TWEAK R (TNFRSF12A), also known as FN14 (fibroblast growth factor-inducible 14) is a receptor for CD255 / TWEAK, the TNF-like weak inducer of apoptosis. CD266 is expressed on endothelial cells, as well as on some cancer tissues, and plays a role in CD255-induced endothelial cell migration, proliferation, and angiogenesis. The CD255-CD266 interaction, or antibody-mediated triggering of CD266 is also able to induce apoptosis and necrosis in CD266-positive cells (including tumor cells), which might have therapeutic potential.
Synonyms FGF-inducible 14, FN14, TNFRSF12A, Tweak receptor
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.