ZNFN1A2 (IKZF2) (51-107) Hamster Monoclonal Antibody [Clone ID: 22F6]

CAT#: AM26777PU-N

ZNFN1A2 (IKZF2) (51-107) hamster monoclonal antibody, clone 22F6, Purified


USD 260.00

2 Weeks*

Size
    • 100 ug

Product Images

Specifications

Product Data
Clone Name 22F6
Applications FC
Recommended Dilution Flow cytometry: Intracellular staining.
Reactivities Human, Mouse
Host Hamster
Isotype IgG
Clonality Monoclonal
Immunogen Peptide coresponding to the amino acids 51-107 of Helios
Specificity This antibody recognizes Helios, a transcription factor expressed in some hematopoietic stem cells, and at high levels in thymic-derived regulatory T cells.
Formulation Phosphate buffered saline (PBS)
State: Purified
State: Liquid Ig fraction
Preservative: 15 mM sodium azide, approx. pH 7.4
Concentration 1.0 mg/ml
Purification Protein-A affinity chromatography
Background Helios, also known as IKZF2 (Ikaros family zinc finger protein 2) is a hematopoietic-specific transcription factor involved in the regulation of lymphocyte development, together with other members of this family, such as Aiolos and Ikaros. Helios forms homo- and heterodimers with these proteins and is thought to function predominantly in early hematopoietic development. Expression of Helios, Aiolos and Ikaros is restricted to cells of the hematopoietic system, whereas other family members, Eos and Pegassus, are more widely expressed. Helios is expressed at early stages of thymocyte development. In mature T cells, Helios has been strongly associated with Treg cells.
Synonyms helios; MGC34330; OTTHUMP00000163964; ZNF1A2; ZNFN1A2
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.