Siglec 7 (SIGLEC7) Mouse Monoclonal Antibody [Clone ID: 6-434]

CAT#: AM26779RP-N

Siglec 7 (SIGLEC7) mouse monoclonal antibody, clone 6-434, PE

Product Images

Surface staining of CD328 in human peripheral blood with anti-CD328 (6-434) PE.

Specifications

Product Data

• Clone Name: 6-434
• Applications: FC
• Recommended Dilution: Flow Cytometry analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human dendritic cells
• Specificity: This antibody recognizes CD328 (Siglec-7), a 75 kDa transmembrane glycoprotein expressed mainly on NK cells, dendritic cells and monocytes.
• Formulation: Phosphate buffered saline (PBS)
  Label: PE
  State: Liquid purified Ig fraction
  Stabilizer: 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA)
  Preservative: 15 mM sodium azide
• Conjugation: PE
• Database Link:
  Entrez Gene 27036 Human
• Background: CD328, also known as Siglec-7 or p75/AIRM1, is a 75 kDa type I transmembrane glycoprotein of sialic acid-binding immunoglobulin-like lectin (Siglec) family. CD328 binds to sialylated glycans with alpha2,6 sialyl and alpha2,8 disyalyl residues and mediates sialic acid-dependent cell-cell binding. As it contains in its intracellular part the immunoreceptor tyrosine-based inhibitory motif (ITIM), it serves as an inhibitory receptor, e.g. of NK cells.
• Synonyms: Siglec-7, QA79 membrane protein, p75, D-siglec, CDw328, AIRM1