CD193 / CCR3 Mouse Monoclonal Antibody [Clone ID: 5E8]

CAT#: AM26800RP-N

CD193 / CCR3 mouse monoclonal antibody, clone 5E8, PE


USD 300.00

2 Weeks*

Size
    • 100 Tests

Product Images

Specifications

Product Data
Clone Name 5E8
Applications FC
Recommended Dilution Flow Cytometry analysis of human blood cells using 10 ?l reagent / 100 ?l of whole blood or 106 cells in a suspension.
Reactivities Human
Host Mouse
Isotype IgG2b
Clonality Monoclonal
Specificity This antibody clone 5E8 recognizes CD193 (chemokine receptor 3), an approximately 41 kDa protein expressed above all in eosinophils and basophils.
Formulation Phosphate buffered saline (PBS) containing 15 mM sodium azide
Label: PE
State: Liquid purified Ig fraction
Label: Conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use.
Conjugation PE
Background CD193 / CCR3 is a G-protein coupled receptor for several chemokines, namely CCL11 (eotaxin), CCL26 (eotaxin-3), CCL7 (MCP-4), or CCL5 (RANTES). It is highly expressed on eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. CD193 is the key eosinophil chemokine receptor responsible for regulation of eosinophil migration and function. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1.
Synonyms C-C chemokine receptor type 3, C-C CKR-3, CC-CKR-3, CCR-3, CKR3, CMKBR3
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.