TSG101 (201-281) Mouse Monoclonal Antibody [Clone ID: 5B7]

CAT#: AM31014PU-N

TSG101 (201-281) mouse monoclonal antibody, clone 5B7, Purified


USD 480.00

2 Weeks*

Size
    • 50 ug

Product Images

Other products for "TSG101"

Specifications

Product Data
Clone Name 5B7
Applications ELISA, IF, IHC, WB
Recommended Dilution ELISA.
Immunofluorescence: 10 µg/ml.
Immunohistochemistry on Paraffin Sections: 5 µg/ml.
Western Blot: 1/500 - 1/1000.
Reactivities Human
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen TSG101 (NP_006283, 201 a.a. ~ 281 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity This antibody reacts to TSG101.
Formulation PBS, pH 7.4
State: Purified
State: Liquid purified Ig fraction
Concentration 0.5 mg/ml
Purification Protein A chromatography
Gene Name Homo sapiens tumor susceptibility 101 (TSG101)
Background The tumor susceptibility gene 101 (TSG101) was first discovered in a screen for potential tumor suppressors. Altered transcripts of this gene have been detected in sporadic breast carcinomas and other malignancies. In mice the gene has been shown to be essential for growth, proliferation and survival of mammary epithelial cells. TSG101 is also a component of the ESCRt-1 complex, a regulator of the vesicular trafficking process. In addition it is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies and is involved the budding of many viruses.
Synonyms TSG10; VPS23
Reference Data
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Endocytosis

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.