STAT4 Mouse Monoclonal Antibody [Clone ID: 1C2-1C12]

CAT#: AM31022PU-N

STAT4 mouse monoclonal antibody, clone 1C2-1C12, Purified

Product Images

STAT4 monoclonal antibody clone 1C2-1C12. Western Blot analysis of STAT4 expression in human liver.

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  STAT4 monoclonal antibody clone 1C2-1C12 Western Blot analysis of STAT4 expression in A-549.

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  Detection limit for recombinant GST tagged STAT4 is approximately 0.3ng/ml as a capture antibody.

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  Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Immunofluorescence of monoclonal antibody to STAT4 on HeLa cell. [antibody concentration 10 ug/ml]

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Specifications

Product Data

• Clone Name: 1C2-1C12
• Applications: ELISA, IF, IHC, IP, WB
• Recommended Dilution: ELISA.
  Immunofluorescence: 10 µg/ml.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Immunoprecipitation.
  Western Blot.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: STAT4 antibody was raised against recombinant protein
• Specificity: This antibody reacts to STAT4.
• Formulation: PBS, pH 7.2
  State: Purified
  State: Liquid purfied Ig fraction
• Concentration: lot specific
• Purification: Protein A chromatography
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens signal transducer and activator of transcription 4 (STAT4), transcript variant 1
• Database Link:
  Entrez Gene 6775 Human
• Background: STAT4 is a transcription factor involved in promoting cell-mediated immunity. It is a key molecule in the intracellular signal transduction cascade activated in response to IL-12 stimulation. Following phosphorylation in response to IL-12 or IFN-alpha STAT4 dimerizes, translocates to the nucleus, and activates gene expression.
• Synonyms: OTTHUMP00000163553; SLEB11

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Jak-STAT signaling pathway