Eph receptor B6 (EPHB6) Mouse Monoclonal Antibody [Clone ID: 5D8]

CAT#: AM31051PU-N

Eph receptor B6 (EPHB6) mouse monoclonal antibody, clone 5D8, Purified

Product Images

EPHB6 monoclonal antibody clone 5D8 Western Blot analysis of EPHB6 expression in PC-12.

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  EPHB6 monoclonal antibody clone 5D8. Western Blot analysis of EPHB6 expression in NIH/3T3.

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  Detection limit for recombinant GST tagged EPHB6 is approximately 0.3ng/ml as a capture antibody.

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  Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Clone Name: 5D8
• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot.
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: EPHB6 antibody was raised against recombinant protein
• Specificity: This antibody reacts to EPHB6.
• Formulation: PBS, pH 7.2
  State: Purified
  State: Liquid purfied Ig fraction
• Concentration: lot specific
• Purification: Protein A chromatography
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens EPH receptor B6 (EPHB6), transcript variant 1
• Database Link:
  Entrez Gene 13848 MouseEntrez Gene 312275 RatEntrez Gene 2051 Human
• Background: EPHB6 belongs to the ephrin receptor kinase family. EPHB6 does not have intrinsic tyrosine kinase activity because six invariant amino acids were have been substituted. Despite its lack of kinase activity, ligand binding results in trans-phosphorylation of EphB6 and the initiation of specific cytoplasmic signaling events.
• Synonyms: Ephrin type-B receptor 6, EPH-6, HEP

Reference Data

• Protein Families: Druggable Genome, Protein Kinase, Transmembrane
• Protein Pathways: Axon guidance