GALT Mouse Monoclonal Antibody [Clone ID: 4C11]

CAT#: AM31056PU-N

GALT mouse monoclonal antibody, clone 4C11, Purified

Product Images

GALT monoclonal antibody clone 4C11 Western Blot analysis of GALT expression in K-562.

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  Detection limit for recombinant GST tagged GALT is approximately 0.3ng/ml as a capture antibody.

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  Human Kidney, Tubules: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Clone Name: 4C11
• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA.
  Immunohistochemistry on Paraffin Sections: 10 µg/ml.
  Western Blot.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: GALT (AAH15045, 1 a.a. ~ 380 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Specificity: This antibody reacts to GALT.
• Formulation: PBS, pH 7.2
  State: Purified
  State: Liquid purfied Ig fraction
• Concentration: lot specific
• Purification: Protein A chromatography
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens galactose-1-phosphate uridylyltransferase (GALT), transcript variant 1
• Database Link:
  Entrez Gene 2592 Human
• Background: Galactose-1-phosphate uridyl transferase (GALT) catalyzes the second step of the Leloir pathway of galactose metabolism, namely the conversion of UDP-glucose + galactose-1-phosphate to glucose-1-phosphate + UDP-galactose. The absence of this enzyme results in classic galactosemia in humans and can be fatal in the newborn period if lactose is not removed from the diet. The pathophysiology of galactosemia has not been clearly defined.
• Synonyms: Gal-1-P uridylyltransferase

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Amino sugar and nucleotide sugar metabolism, Galactose metabolism, Metabolic pathways