KAP1 (TRIM28) Mouse Monoclonal Antibody [Clone ID: 1D11]

CAT#: AM31085PU-N

KAP1 (TRIM28) mouse monoclonal antibody, clone 1D11, Purified


USD 480.00

2 Weeks*

Size
    • 50 ug

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Specifications

Product Data
Clone Name 1D11
Applications ELISA, IHC, WB
Recommended Dilution ELISA.
Immunohistochemistry on Paraffin Sections: 5 µg/ml.
Western Blot.
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen TRIM28 (AAH04978, 379 a.a. ~ 524 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity This antibody reacts to TRIM28.
Formulation PBS, pH 7.2
State: Purified
State: Liquid purfied Ig fraction
Concentration 0.21 mg/ml
Purification Protein A chromatography
Gene Name Homo sapiens tripartite motif containing 28 (TRIM28)
Background TIF1beta is a member of the Transcriptional Intermediary Factor 1 (TIF1) subfamily. TIF1beta contains a RING finger, B box, Coiled coil, PHD/TTC, and bromodomain. TIF1beta is a corepressor for Kruppel-associated box (KRAB)-domain-containing zinc finger proteins and plays a critical role in early embryogenesis. TIF1beta acts as a transcriptional mediator by binding liganded nuclear receptors, including retinoic acid (RAR), retinoid X (RXR) and estrogen (ER) receptors. TIF1beta associates with both heterochromatin and euchromatin, causing gene silencing by both HP1 binding and histone deacetylation.
Synonyms TIF1 beta, TIF1B, KAP1, KAP-1, KRIP1, KRIP-1, RNF96, RING finger protein 96
Reference Data
Protein Families Protein Kinase, Stem cell - Pluripotency, Transcription Factors

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.